Isn't moving from Wisconsin to North Carolina a distinctly eastward trip?
Tell us more on what you want to do. Is this a pavement trip? A mountain bike trip? A gravel and dirt road trip? Probably some combination of the above, but let's at least talk percentages.
Do you have a bike or are you going to buy one?
Have you been over to visit the website of the Adventure Cycling Association?
Read around on Crazy Guy on a Bike?
Checked the touring sections of the the major bike boards?