How much time do you have?
For longer tours, the PA state forests in N Central PA offer tons of possibilities. Also the Mongehelia National Forest in WV has a lot to offer... for rail trails, search Greenbrier RT and Durbin/Glady rail trail.
I do a lot of weekend stuff. Drive Fri night, Ride Sat, camp Sat night, ride Sun and drive back home Sun late afternoon.
Some sample Weekend PA tours:
1. Twin Sisters
http://maps.google.com/maps?f=q&source=s_q&hl=en&geocode=&q=http:%2F%2Fhome.windstream.net%2FJHLange%2Fssf.kml&ie=UTF8&t=p&z=102. Elk Path
http://maps.google.com/maps?f=q&source=s_q&hl=en&geocode=&q=http:%2F%2Fhome.windstream.net%2FJHLange%2Fssf.kml&ie=UTF8&t=p&z=10